Home > 分離済み変異体 > tm6048

分離済み変異体

Allele Name		tm6048
Balance		Not Required
OutCross		Not Accepted
Sequence Name		ZC155.3
Gene Name		morc-1
Worm Base	Allele Name	tm6048
	Gene Name	morc-1
	Sequence	ZC155.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		7929/7930-8338/8339 (409 bp deletion)
Chromosome		III
Putative gene structure		complement(join(5616..5684, 5734..5973, 6023..6714, 6763..7401, 7446..7587, 7663..8249, 8301..8389, 8445..8524))
Map position		-2.01
Balancer
Map position of balancer
Sequence of primers		ExtFwd:ACAGCTTCCAAATCCCACAC,ExtRev:ATGCTGCATTGGCCTAAAGT,IntFwd:GTCCACATCACCTGATCCCT,IntRev:TTGTCCTCTGTTCGGGCCTC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Kirshner JA, Picard CL, Weiser NE, Mehta N, Feng S, Murphy VN, Vakhnovetsky A, Alessi AF, Xiao C, Inoki K, El Mouridi S, Frøkjær-Jensen C, Jacobsen SE, Kim JK. Regulation of MORC-1 is key to the CSR-1-mediated germline gene licensing mechanism in C. elegans. Sci Adv 2025 11(25) eado4170  [ PubMed ID = 40540580 ] [ RRC reference ] Mazzetto M, Gonzalez LE, Sanchez N, Reinke V. Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis. Genome Res 2024 34(1) 57-69  [ PubMed ID = 38164610 ] [ RRC reference ] Spracklin G, Fields B, Wan G, Becker D, Wallig A, Shukla A, Kennedy S. The RNAi Inheritance Machinery of Caenorhabditis elegans. Genetics 2017 206(3) 1403-1416  [ PubMed ID = 28533440 ] [ RRC reference ] Weiser NE, Yang DX, Feng S, Kalinava N, Brown KC, Khanikar J, Freeberg MA, Snyder MJ, Csankovszki G, Chan RC, Gu SG, Montgomery TA, Jacobsen SE, Kim JK. MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality. Dev Cell 2017 41(4) 408-423.e7  [ PubMed ID = 28535375 ] [ RRC reference ]