分離済み変異体

tm6048

Allele Nametm6048
BalanceNot Required
OutCrossNot Accepted
Sequence NameZC155.3
Gene Namemorc-1
Worm BaseAllele Name tm6048
Gene Name morc-1
Sequence ZC155.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7929/7930-8338/8339 (409 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(5616..5684, 5734..5973, 6023..6714, 6763..7401, 7446..7587, 7663..8249, 8301..8389, 8445..8524))
Map position-2.01
Balancer
Map position of balancer
Sequence of primersExtFwd:ACAGCTTCCAAATCCCACAC,ExtRev:ATGCTGCATTGGCCTAAAGT,IntFwd:GTCCACATCACCTGATCCCT,IntRev:TTGTCCTCTGTTCGGGCCTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Spracklin G, Fields B, Wan G, Becker D, Wallig A, Shukla A, Kennedy S.
The RNAi Inheritance Machinery of Caenorhabditis elegans.
Genetics 2017 206(3) 1403-1416 
[ PubMed ID = 28533440 ] [ RRC reference ]

Weiser NE, Yang DX, Feng S, Kalinava N, Brown KC, Khanikar J, Freeberg MA, Snyder MJ, Csankovszki G, Chan RC, Gu SG, Montgomery TA, Jacobsen SE, Kim JK.
MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality.
Dev Cell 2017 41(4) 408-423.e7 
[ PubMed ID = 28535375 ] [ RRC reference ]