分離済み変異体

tm5921

Allele Nametm5921
BalanceCompleted
OutCrossNot Accepted
Sequence NameF15D3.7
Gene NameF15D3.7
Worm BaseAllele Name tm5921 (x1)
Gene Name F15D3.7
Sequence F15D3.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 38768/38769-38981/38982 (213 bp deletion)
ChromosomeI
Putative gene structurejoin(38474..38599, 38649..38863, 38922..39309)
Map position9.24
BalancerhT2,hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:GCGCGTTGTTTAGCGGCACA,IntFwd:GCGGCACAGGAAGCGTTATT,IntRev:AAGCCTTCAATCCATGCGGT,ExtRev:GGCGATACCCAATCCAACAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Thapa P, Chikale RV, Szulc NA, Pandrea MT, Sztyler A, Jaggi K, Niklewicz M, Serwa RA, Hoppe T, Pokrzywa W.
HSP70 inhibits CHIP E3 ligase activity to maintain germline function in Caenorhabditis elegans.
J Biol Chem 2024 300(11) 107864 
[ PubMed ID = 39384041 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]