分離済み変異体

tm5866

Allele Nametm5866
BalanceNot Required
OutCrossNot Accepted
Sequence NameY64G10A.6
Gene NameY64G10A.6
Worm BaseAllele Name tm5866
Gene Name Y64G10A.6
Sequence Y64G10A.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 48565/48566-TGTTTTG-49127/49128 (562 bp deletion + 7 bp insertion)
ChromosomeIV
Putative gene structurejoin(45574..45889, 47119..47396, 48214..48400, 48456..48577, 48818..49070, 49126..49216, 49300..49475, 49843..49949, 52009..52217, 52609..53314, 54093..54188)
Map position11.69
Balancer
Map position of balancer
Sequence of primersIntRev:TCCCTGTATCTCCTACTCAC,ExtRev:GATTGCGTAGGTGTGCCTGA,IntFwd:CTTATAAAACCGCAGGCCTT,ExtFwd:CATGTTCTGCCAGTGCCATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Kramer TS, Wan FK, Pugliese SM, Atanas AA, Hiser AW, Luo J, Bueno E, Flavell SW.
Neural Sequences Underlying Directed Turning in C. elegans.
bioRxiv 2024   
[ PubMed ID = 39149398 ] [ RRC reference ]

Omi S, Pujol N.
unc-119 mutants have an increased fungal spore adhesion that is not rescued by Cb-unc-119.
MicroPubl Biol 2021 2021  
[ PubMed ID = 33543000 ] [ RRC reference ]

Flynn SM, Chen C, Artan M, Barratt S, Crisp A, Nelson GM, Peak-Chew SY, Begum F, Skehel M, de Bono M.
MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity.
Nat Commun 2020 11(1) 2099 
[ PubMed ID = 32350248 ] [ RRC reference ]

Chen C, Itakura E, Nelson GM, Sheng M, Laurent P, Fenk LA, Butcher RA, Hegde RS, de Bono M.
IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses.
Nature 2017 542(7639) 43-48 
[ PubMed ID = 28099418 ] [ RRC reference ]