分離済み変異体

tm5539

Allele Nametm5539
BalanceNot Required
OutCrossNot Accepted
Sequence NameT01B6.3
Gene Nameaakg-4
Worm BaseAllele Name tm5539
Gene Name aakg-4
Sequence T01B6.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 6616/6617-7021/7022 (405 bp deletion)
ChromosomeX
Putative gene structureT01B6.3a=complement(join(6346..6492, 6543..6824, 7521..7610, 8273..8347, 8400..8463, 8875..8951, 9063..9206, 9265..9365, 9659..9728, 9778..10039, 10233..10318)); T01B6.3b=complement(join(6346..6492, 6543..6839))
Map position-15.79
Balancer
Map position of balancer
Sequence of primersIntRev:CAGGAGTTATCATTCAGGCT,IntFwd:GAAGATGATCGGTCCTCGGT,ExtRev:AGTCTCTGACACGCCGAGTT,ExtFwd:GGCATACTCGATGTGCTAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Scanlon DM, Tullet JMA.
Allosteric regulation of C. elegans AMP-activated protein kinase.
MicroPubl Biol 2022 2022  
[ PubMed ID = 35622498 ] [ RRC reference ]

Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D.
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
PLoS Genet 2014 10(2) e1004109 
[ PubMed ID = 24516399 ] [ RRC reference ]