分離済み変異体

tm5532

Allele Nametm5532
BalanceCompleted
OutCrossNot Accepted
Sequence NameY50D4A.2
Gene Namewrb-1
Worm BaseAllele Name tm5532 (x1)
Gene Name wrb-1
Sequence Y50D4A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 16047/16048-GGAACTTGAAAATCGA-16587/16588 (540 bp deletion + 16 bp insertion)
ChromosomeV
Putative gene structurejoin(16234..16344, 16392..16758, 16815..16915)
Map position-19.85
BalancernT1
Map position of balancer
Sequence of primersIntRev:GGTCCGATTTTCTGAATGTC,IntFwd:GCGTGATGTTTCCGTCGTGA,ExtRev:CGAGTCGAGAGAAATAGTCA,ExtFwd:ATTCGCTGGCTGGAGCAGTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Franziscus CA, Ritz D, Kappel NC, Solinger JA, Schmidt A, Spang A.
The protein tyrosine phosphatase PPH-7 is required for fertility and embryonic development in C. elegans at elevated temperatures.
FEBS Open Bio 2024 14(3) 390-409 
[ PubMed ID = 38320757 ] [ RRC reference ]

Raj D, Billing O, Podraza-Farhanieh A, Kraish B, Hemmingsson O, Kao G, Naredi P.
Alternative redox forms of ASNA-1 separate insulin signaling from tail-anchored protein targeting and cisplatin resistance in C. elegans.
Sci Rep 2021 11(1) 8678 
[ PubMed ID = 33883621 ] [ RRC reference ]