分離済み変異体

tm5409

Allele Nametm5409
BalanceNot Required
OutCrossNot Accepted
Sequence NameF46B6.3
Gene Namesmg-4
Worm BaseAllele Name tm5409
Gene Name smg-4
Sequence F46B6.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7939/7940-CAAGTTTCCGAATTTGCGTCCTGCTTCTCCCC-8277/8278 (338 bp deletion + 32 bp insertion)
ChromosomeV
Putative gene structurecomplement(join(7222..7353, 7692..8200, 8253..8578, 8632..8771))
Map position2.2
Balancer
Map position of balancer
Sequence of primersIntFwd:GCCGTGTATCGGTTTCCTTA,ExtFwd:TAGAAGATGGTGCCGTTCGT,IntRev:GACCGATTCAAAAGACGGTC,ExtRev:TCCGGTCTGCACCCGTTAAA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH.
Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation.
Proc Natl Acad Sci U S A 2020 117(1) 656-667 
[ PubMed ID = 31754030 ] [ RRC reference ]

Sakaki K, Yoshina S, Shen X, Han J, DeSantis MR, Xiong M, Mitani S, Kaufman RJ.
RNA surveillance is required for endoplasmic reticulum homeostasis.
Proc Natl Acad Sci U S A 2012 109(21) 8079-84 
[ PubMed ID = 22562797 ] [ RRC reference ]