分離済み変異体

tm5375

Allele Nametm5375
BalanceCompleted
OutCrossNot Accepted
Sequence NameZK512.5
Gene Namesec-16
Worm BaseAllele Name tm5375 (x1)
Gene Name sec-16
Sequence ZK512.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14858/14859-15198/15199 (340 bp deletion)
ChromosomeIII
Putative gene structurejoin(13445..13459, 13833..13872, 13927..14026, 14086..14253, 14299..14893, 14940..15052, 15098..15536, 15586..15741, 15787..16062, 16109..16314, 16362..17433, 17489..17638, 17691..17976, 18026..18108)
Map position0.17
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:CGCCGTGTTGGCACTAAAGT,ExtRev:AACCAGACTCGGATGTCCCA,IntFwd:GACCTCAATTTGCCCCTTCT,IntRev:CGAGGCATTTGTCAGCAGTG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Ihara S, Nakayama S, Murakami Y, Suzuki E, Asakawa M, Kinoshita T, Sawa H.
PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis.
J Cell Sci 2017 130(3) 602-613 
[ PubMed ID = 27980068 ] [ RRC reference ]