分離済み変異体

tm5271

Allele Nametm5271
BalanceCompleted
OutCrossNot Accepted
Sequence NameW01B6.9
Gene Namendc-80
Worm BaseAllele Name tm5271 (x1)
Gene Name ndc-80
Sequence W01B6.9
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 27445/27446-27679/27680 (234 bp deletion)
ChromosomeIV
Putative gene structurejoin(27278..27390, 27438..27840, 27893..28122, Z70718.1:105..162, Z70718.1:210..569, Z70718.1:648..751, Z70718.1:799..927, Z70718.1:1000..1318, Z70718.1:1367..1423)
Map position4.49
BalancernT1 [qIs51]
Map position of balancer
Sequence of primersIntRev:GTGTGTCCTCACTGACAGCA,IntFwd:GCGAGTGCAGCGTCTCTGTA,ExtRev:CCCAGTATGAAGAACTGGGA,ExtFwd:CTCCGGAAATCAGTTTCCTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Ouzounidis VR, Green M, van Capelle CC, Gebhardt C, Crellin H, Finlayson C, Prevo B, Cheerambathur DK.
The outer kinetochore components KNL-1 and Ndc80 complex regulate axon and neuronal cell body positioning in the C. elegans nervous system.
Mol Biol Cell 2024 35(6) ar83 
[ PubMed ID = 38656792 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Cheerambathur DK, Gassmann R, Cook B, Oegema K, Desai A.
Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation.
Science 2013 342(6163) 1239-42 
[ PubMed ID = 24231804 ] [ RRC reference ]