分離済み変異体

tm526

Allele Nametm526
BalanceNot Required
OutCrossNot Accepted
Sequence NameF46E10.8
Gene Nameubh-1
Worm BaseAllele Name tm526
Gene Name ubh-1
Sequence F46E10.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. Inoue: long defecation cycle, reduced brood size, Gro.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1906/1907-GAAAATCCGAACGTTNNNATTAAAATCCGAA-2383/2384 (477 bp deletion + 31 bp insertion)
ChromosomeV
Putative gene structurecomplement(join(2025..2164, 2211..2330, 2376..2453, 2899..2971, 3021..3092, 3146..3262, 3333..3383))
Map position-0.03
Balancer
Map position of balancer
Sequence of primersExtFwd:TGCCATCCTCCTGTTGCGCT,IntFwd:TAGCCATCTGGAAGCTGTTT,IntRev:CTCTTGCTGCGAGAGCCAGT,ExtRev:TCTGCAACGACGACACGTAA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Nagata A, Itoh F, Sasho A, Sugita K, Suzuki R, Hinata H, Shimoda Y, Suzuki E, Maemoto Y, Inagawa T, Fujikawa Y, Ikeda E, Fujii C, Inoue H.
The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.
J Biol Chem 2020 295(27) 9105-9120 
[ PubMed ID = 32371398 ] [ RRC reference ]