分離済み変異体

tm521

Allele Nametm521
BalanceCompleted
OutCrossNot Accepted
Sequence NameF26A3.3
Gene Nameego-1
Worm BaseAllele Name tm521 (x1)
Gene Name ego-1
Sequence F26A3.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. G. Ruvkun: no effect on dauer arrest.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15811/15812-16439/16440 (628 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(6032..6192, 6240..6359, 6410..6659, 6910..7490, 7543..7678, 7731..7910, 7956..8227, 8273..8474, 8530..8987, 9035..9146, 9197..9559, 9604..9783, 9861..10403, 10452..10718, 10780..10959, 11038..11181, 11230..11352, 11428..11748, 11799..11957, 12052..12169, 13141..13225, 13278..13647, 13697..14226, 14274..14412, 14461..14640, 14686..15159, 15227..15669, 15718..15829, 15878..16255, 16300..17481, 17527..17661, 17740..17880, 17930..18304, 18349..18513, 18557..18664))
Map position2.21
BalancerhT2 [bli-4(e937) let-? qIs48],tmC18[tmIs1200]
Map position of balancer
Sequence of primersExtFwd:CAGGTACTCTTTCAGCTCTT,IntFwd:GGTGGAATCATTTCGCCAGT,ExtRev:GGAATATGGCACCGATTCCT,IntRev:CTCCACTACTACACGAAAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Dejima K, Yoshida K, Mitani S.
Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans.
EMBO Rep 2025 26(18) 4503-4531 
[ PubMed ID = 40789965 ] [ RRC reference ]