分離済み変異体

tm5180

Allele Nametm5180
BalanceNot Required
OutCrossNot Accepted
Sequence NameM04D8.1
Gene Nameins-21
Worm BaseAllele Name tm5180
Gene Name ins-21
Sequence M04D8.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 6338/6339-7139/7140 (801 bp deletion)
ChromosomeIII
Putative gene structurejoin(6682..6874, 6922..6998)
Map position1.57
Balancer
Map position of balancer
Sequence of primersExtRev:CTCAAGAAGCCGTAATGTAG,IntFwd:CGCTTATCGGTTTAAAGGGT,ExtFwd:CAGGGCACTGCTTGACCAAT,IntRev:ACCCCCAATGACTGATTCTT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Nakayama A, Watanabe M, Yamashiro R, Kuroyanagi H, Matsuyama HJ, Oshima A, Mori I, Nakano S.
A hyperpolarizing neuron recruits undocked innexin hemichannels to transmit neural information in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2024 121(21) e2406565121 
[ PubMed ID = 38753507 ] [ RRC reference ]

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q.
An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.
PLoS Genet 2014 10(3) e1004225 
[ PubMed ID = 24675767 ] [ RRC reference ]

Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M.
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.
EMBO J 2013 32(12) 1745-60 
[ PubMed ID = 23665919 ] [ RRC reference ]