分離済み変異体

tm5176

Allele Nametm5176
BalanceNot Required
OutCrossNot Accepted
Sequence NameT01G1.1
Gene Nameklp-12
Worm BaseAllele Name tm5176
Gene Name klp-12
Sequence T01G1.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [F54E12] 8286/8287-[F54E12] 9507/9508 (1221 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(7667..7895, 7951..8543, 8633..8839, 9242..9378, 9659..9907, 10707..10889, 12226..12403, 12453..12548, 12871..12958, 3425..3500, 3651..3757, 7984..8121, 8566..9284, 9334..9618, 9845..10247, 10318..10585, 10636..10751, 10799..11083, 11130..11453, 12064..12286, 12334..12432))
Map position4.96
Balancer
Map position of balancer
Sequence of primersExtFwd:GATGCTTACTAAGCGACTGT,IntFwd:GCGTCTATAACGTAAGCTCT,ExtRev:TAGTGACGCATGTGTACCGT,IntRev:CTCCAATCGGAGCTCCGAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Taguchi S, Nakano J, Imasaki T, Kita T, Saijo-Hamano Y, Sakai N, Shigematsu H, Okuma H, Shimizu T, Nitta E, Kikkawa S, Mizobuchi S, Niwa S, Nitta R.
Structural model of microtubule dynamics inhibition by kinesin-4 from the crystal structure of KLP-12 -tubulin complex.
Elife 2022 11  
[ PubMed ID = 36065637 ] [ RRC reference ]

De Arras L, Seng A, Lackford B, Keikhaee MR, Bowerman B, Freedman JH, Schwartz DA, Alper S.
An evolutionarily conserved innate immunity protein interaction network.
J Biol Chem 2013 288(3) 1967-78 
[ PubMed ID = 23209288 ] [ RRC reference ]