Home > 分離済み変異体 > tm5155

分離済み変異体

Allele Name		tm5155
Balance		Not Required
OutCross		Not Accepted
Sequence Name		T10D4.13
Gene Name		ins-19
Worm Base	Allele Name	tm5155
	Gene Name	ins-19
	Sequence	T10D4.13
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		9512/9513-9992/9993 (480 bp deletion)
Chromosome		II
Putative gene structure		complement(join(9371..9498,9542..9737))
Map position		-8.42
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GGTACCTACGTGCCTAGGTT,IntFwd:TTACTACGTGCCTACGCGAC,ExtRev:TCGGGAAGAATTCGAGGTAG,IntRev:GAAGGTTAGGCTCAGGCTAA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Zhou S, Novak KE, Kaletsky R, Weng Y, Ange JS, Stevenson ME, Toraason E, Zhang Y, Zhang W, Dong MQ, Murphy CT. Body-to-brain insulin and Notch signaling regulates memory through neuronal CREB activity. Nat Aging 2025 5(7) 1232-1248  [ PubMed ID = 40425807 ] [ RRC reference ] Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. PLoS Genet 2014 10(3) e1004225  [ PubMed ID = 24675767 ] [ RRC reference ] Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M. Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J 2013 32(12) 1745-60  [ PubMed ID = 23665919 ] [ RRC reference ]