分離済み変異体

tm5092

Allele Nametm5092
BalanceNot Required
OutCrossNot Accepted
Sequence NameY40B1B.6
Gene Namespr-5
Worm BaseAllele Name tm5092
Gene Name spr-5
Sequence Y40B1B.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21031/21032-21208/21209 (177 bp deletion)
ChromosomeI
Putative gene structurejoin(16662..16740, 17501..17730, 19395..19700, 20983..21625, 22437..22635, 23692..23868, 25405..25782, 28224..28524)
Map position20.64
Balancer
Map position of balancer
Sequence of primersIntFwd:GTAGTGAGAGCTCACACTAC,ExtFwd:ATTTACCACTCCGCGTGATA,IntRev:CGCCACTCCATTCTCCTTAT,ExtRev:TCACTAACATCTCGCCGCCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Wan QL, Meng X, Dai W, Luo Z, Wang C, Fu X, Yang J, Ye Q, Zhou Q.
N6-methyldeoxyadenine and histone methylation mediate transgenerational survival advantages induced by hormetic heat stress.
Sci Adv 2021 7(1)  
[ PubMed ID = 33523838 ] [ RRC reference ]

Abay-Nørgaard S, Attianese B, Boreggio L, Salcini AE.
Regulators of H3K4 methylation mutated in neurodevelopmental disorders control axon guidance in Caenorhabditis elegans.
Development 2020 147(15)  
[ PubMed ID = 32675280 ] [ RRC reference ]