分離済み変異体

tm5068

Allele Nametm5068
BalanceNot Required
OutCrossNot Accepted
Sequence NameC47E12.3
Gene NameC47E12.3
Worm BaseAllele Name tm5068
Gene Name C47E12.3
Sequence C47E12.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 32448/32449-TTTTTTGACGCATATTTTATTTTTTTTTTGACGCATATTTT-32711/32712 (263 bp deletion + 41 bp insertion)
ChromosomeIV
Putative gene structurecomplement(join(30369..30581, 30637..31062, 31107..31381, 31434..31886, 32404..32483, 32527..32663, 32706..32825, 32874..32876))
Map position4.46
Balancer
Map position of balancer
Sequence of primersIntRev:TTCGGAGGAGAGCTGACGTG,IntFwd:ACATGTTGGGCTATCATGAG,ExtRev:CCTTCTGCCATGAGGATCGT,ExtFwd:CAGGGGCTTGAATCTGCACA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Taylor CA, Maor-Nof M, Metzl-Raz E, Hidalgo A, Yee C, Gitler AD, Shen K.
Histone deacetylase inhibition expands cellular proteostasis repertoires to enhance neuronal stress resilience.
bioRxiv 2024   
[ PubMed ID = 39229034 ] [ RRC reference ]

Ghenea S, Chiritoiu M, Tacutu R, Miranda-Vizuete A, Petrescu SM.
Targeting EDEM protects against ER stress and improves development and survival in C. elegans.
PLoS Genet 2022 18(2) e1010069 
[ PubMed ID = 35192599 ] [ RRC reference ]