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分離済み変異体

Allele Name		tm5052
Balance		Not Required
OutCross		Not Accepted
Sequence Name		R13A1.4
Gene Name		unc-8
Worm Base	Allele Name	tm5052
	Gene Name	unc-8
	Sequence	R13A1.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		9690/9691-CT-9887/9888 (197 bp deletion + 2 bp insertion)
Chromosome		IV
Putative gene structure		join(7733..7770, 8144..8201, 8772..8885, 9401..9549, 9600..9742, 9787..9869, 9926..10017, 10064..10202, 10287..10373, 10416..10553, 10598..10699, 10747..10904, 10949..11049, 11113..11273, 11319..11411, 11456..11573, 11946..12089, 12136..12275, 12412..12507, 12559..12738)
Map position		3.29
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CTAGTGGAACACGACGCAAT,IntFwd:TGGGGCCCTAATAATTTCGA,ExtRev:ACCCTCTAAGTCTTCGTCAT,IntRev:CCTGGCTTCATACTGTCACT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Cuentas-Condori A, Chen S, Krout M, Gallik KL, Tipps J, Gailey C, Flautt L, Kim H, Mulcahy B, Zhen M, Richmond JE, Miller DM 3rd. The epithelial Na+ channel UNC-8 promotes an endocytic mechanism that recycles presynaptic components to new boutons in remodeling neurons. Cell Rep 2023 42(11) 113327  [ PubMed ID = 37906594 ] [ RRC reference ] Miller-Fleming TW, Petersen SC, Manning L, Matthewman C, Gornet M, Beers A, Hori S, Mitani S, Bianchi L, Richmond J, Miller DM. The DEG/ENaC cation channel protein UNC-8 drives activity-dependent synapse removal in remodeling GABAergic neurons. Elife 2016 5   [ PubMed ID = 27403890 ] [ RRC reference ]