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分離済み変異体

Allele Name		tm5034
Balance		Completed
OutCross		Not Accepted
Sequence Name		F08G5.1
Gene Name		dsb-1
Worm Base	Allele Name	tm5034 (x1)
	Gene Name	dsb-1
	Sequence	F08G5.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		3074/3075-3412/3413 (338 bp deletion)
Chromosome		IV
Putative gene structure		join(2838..2935, 2985..3151, 3200..3582, 3633..3950, 4009..4101)
Map position		5.92
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		ExtFwd:GTAAAAGTGATGGATGGGTC,IntFwd:TTGAGGTCCAATGAGGTCGA,ExtRev:TGCGTTGGTGATCCTTGACT,IntRev:AGATCGCATCATTCCAACCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Lascarez-Lagunas LI, Martinez-Garcia M, Nadarajan S, Diaz-Pacheco BN, Berson E, Colaiácovo MP. Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans. PLoS Genet 2023 19(1) e1010627  [ PubMed ID = 36706157 ] [ RRC reference ] Guo H, Stamper EL, Sato-Carlton A, Shimazoe MA, Li X, Zhang L, Stevens L, Tam KCJ, Dernburg AF, Carlton PM. Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity. Elife 2022 11   [ PubMed ID = 35758641 ] [ RRC reference ] Stamper EL, Rodenbusch SE, Rosu S, Ahringer J, Villeneuve AM, Dernburg AF. Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint. PLoS Genet 2013 9(8) e1003679  [ PubMed ID = 23990794 ] [ RRC reference ]