分離済み変異体

tm5013

Allele Nametm5013
BalanceNot Required
OutCrossNot Accepted
Sequence NameF52E1.7
Gene Namehsp-17
Worm BaseAllele Name tm5013
Gene Name hsp-17
Sequence F52E1.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 5693/5694-6113/6114 (420 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(5496..5660, 5922..6159, 6470..6516))
Map position1.37
Balancer
Map position of balancer
Sequence of primersExtRev:GATTCGTCGGAGTAGATGTT,IntRev:AGCAGGGAGTGTCAACTCAG,ExtFwd:AGTGAAGAGGCCATCCATGT,IntFwd:AGGCCATCCATGTTCCCATA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Strauch A, Rossa B, Köhler F, Haeussler S, Mühlhofer M, Rührnößl F, Körösy C, Bushman Y, Conradt B, Haslbeck M, Weinkauf S, Buchner J.
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions.
J Biol Chem 2023 299(1) 102753 
[ PubMed ID = 36442512 ] [ RRC reference ]

Earley BJ, Cubillas C, Warnhoff K, Ahmad R, Alcantar A, Lyon MD, Schneider DL, Kornfeld K.
Cadmium hijacks the high zinc response by binding and activating the HIZR-1 nuclear receptor.
Proc Natl Acad Sci U S A 2021 118(42)  
[ PubMed ID = 34649987 ] [ RRC reference ]