Home > 分離済み変異体 > tm5011

分離済み変異体

Allele Name		tm5011
Balance		Not Required
OutCross		Not Accepted
Sequence Name		B0218.1
Gene Name		faah-1
Worm Base	Allele Name	tm5011
	Gene Name	faah-1
	Sequence	B0218.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13263/13264-TG-13778/13779 (515 bp deletion + 2 bp insertion)
Chromosome		IV
Putative gene structure		join(12995..13069, 13270..13717, 14044..14399, 14451..14889, 15048..15236, 15303..15514)
Map position		3.65
Balancer
Map position of balancer
Sequence of primers		IntRev:CCGTCGTAGATTGTCTACGT,IntFwd:CGCACTTCCCTCAAACGAAT,ExtRev:CTAATCGTGCGTGCTCTCTC,ExtFwd:CCTCACAATCAGTACCATGG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Park S, Jin Y, Chisholm AD. Phospholipid biogenesis maintains neuronal integrity during aging and axon regeneration. Genetics 2025 231(1)   [ PubMed ID = 40557979 ] [ RRC reference ] Ruan M, Xu F, Li N, Yu J, Teng F, Tang J, Huang C, Zhu H. Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1. PLoS Biol 2024 22(10) e3002841  [ PubMed ID = 39436954 ] [ RRC reference ] Zhang T, Xie L, Guo Y, Wang Z, Guo X, Liu R, Jin Q, Chang M, Wang X. 4,4-Dimethylsterols Reduces Fat Accumulation via Inhibiting Fatty Acid Amide Hydrolase In Vitro and In Vivo. Research (Wash D C) 2024 7 0377  [ PubMed ID = 38812531 ] [ RRC reference ] Pastuhov SI, Matsumoto K, Hisamoto N. Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32. Genes Cells 2016 21(7) 696-705  [ PubMed ID = 27193416 ] [ RRC reference ] Harrison N, Lone MA, Kaul TK, Reis Rodrigues P, Ogungbe IV, Gill MS. Characterization of N-acyl phosphatidylethanolamine-specific phospholipase-D isoforms in the nematode Caenorhabditis elegans. PLoS One 2014 9(11) e113007  [ PubMed ID = 25423491 ] [ RRC reference ] Pastuhov SI, Fujiki K, Nix P, Kanao S, Bastiani M, Matsumoto K, Hisamoto N. Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. Nat Commun 2012 3 1136  [ PubMed ID = 23072806 ] [ RRC reference ]