Home > 分離済み変異体 > tm5004

分離済み変異体

Allele Name		tm5004
Balance		Not Required
OutCross		Not Accepted
Sequence Name		T23G4.3
Gene Name		nyn-1
Worm Base	Allele Name	tm5004
	Gene Name	nyn-1
	Sequence	T23G4.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		14856/14857-15626/15627 (770 bp deletion)
Chromosome		IV
Putative gene structure		complement(join(13395..13637, 13824..14072, 14118..14249, 14312..14514, 14576..15206))
Map position		10.57
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CGCGAGACCAGAAACAACGT,ExtRev:CGCCCAGGATGTTGATAATC,IntFwd:TGACTTTGTGGCCACGAATC,IntRev:TAGGCTTGCCGGCAAGCTTG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Lowe DD, Newman M, Ruvkun G, Kennedy SG. The microRNA miR-243 directs poly(UG) modification of a somatic mRNA in C. elegans. MicroPubl Biol 2025 2025   [ PubMed ID = 40880989 ] [ RRC reference ] Uebel CJ, Anderson DC, Mandarino LM, Manage KI, Aynaszyan S, Phillips CM. Distinct regions of the intrinsically disordered protein MUT-16 mediate assembly of a small RNA amplification complex and promote phase separation of Mutator foci. PLoS Genet 2018 14(7) e1007542  [ PubMed ID = 30036386 ] [ RRC reference ] Tsai HY, Chen CC, Conte D Jr, Moresco JJ, Chaves DA, Mitani S, Yates JR 3rd, Tsai MD, Mello CC. A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi. Cell 2015 160(3) 407-19  [ PubMed ID = 25635455 ] [ RRC reference ]