Home > 分離済み変異体 > tm495

分離済み変異体

Allele Name		tm495
Balance		Not Required
OutCross		Not Accepted
Sequence Name		K11D2.2
Gene Name		asah-1
Worm Base	Allele Name	tm495
	Gene Name	asah-1
	Sequence	K11D2.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		6222/6223-cata-6695/6696 (473 bp deletion, 4 bp addition)
Chromosome		I
Putative gene structure		join(4471..4613, 5445..6079, 6243..6436, 6648..6857)
Map position		13.24
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GATGAATCGTGACTCCTTAG,ExtRev:AATCATTGCGTATATGAGAATGTT,IntFwd:GGGCTCCACTGAAGTCTACC,IntRev:CCAATCTACCATGGATAGCATT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Peters L, Drechsler M, Herrera MA, Liu J, Pees B, Jarstorff J, Czerwinski A, Lubbock F, Angelidou G, Salzer L, Moors KA, Paczia N, Shi YM, Schulenburg H, Kaleta C, Witting M, Liebeke M, Campopiano DJ, Bode HB, Dierking K. Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans. Nat Commun 2025 16(1) 5151  [ PubMed ID = 40461452 ] [ RRC reference ] Alexander KD, Ramachandran S, Biswas K, Lambert CM, Russell J, Oliver DB, Armstrong W, Rettler M, Liu S, Doitsidou M, Bénard C, Walker AK, Francis MM. The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling. Nat Commun 2023 14(1) 7520  [ PubMed ID = 37980357 ] [ RRC reference ] Wang W, Sherry T, Cheng X, Fan Q, Cornell R, Liu J, Xiao Z, Pocock R. An intestinal sphingolipid confers intergenerational neuroprotection. Nat Cell Biol 2023 25(8) 1196-1207  [ PubMed ID = 37537365 ] [ RRC reference ] Menzel R, Menzel S, Swain SC, Pietsch K, Tiedt S, Witczak J, Stürzenbaum SR, Steinberg CE. The Nematode Caenorhabditis elegans, Stress and Aging: Identifying the Complex Interplay of Genetic Pathways Following the Treatment with Humic Substances. Front Genet 2012 3 50  [ PubMed ID = 22529848 ] [ RRC reference ]