Home > 分離済み変異体 > tm4948

分離済み変異体

Allele Name		tm4948
Balance		Completed
OutCross		Not Accepted
Sequence Name		C34C6.6
Gene Name		prx-5
Worm Base	Allele Name	tm4948 (x1)
	Gene Name	prx-5
	Sequence	C34C6.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		32467/32468-32904/32905 (437 bp deletion)
Chromosome		II
Putative gene structure		join(32563..32662, 32712..32896, 32945..33289, 33338..33568, 33714..33803, 33856..34319, 34366..34459)
Map position		0.85
Balancer		mIn1,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primers		IntRev:GCATCCAAGAATCTAGCCTC,ExtRev:GCCAACTTGAGAGAGTCGAC,IntFwd:CTACACTGGGGCCCACTTAT,ExtFwd:CGACCTCCGTTGTTCCTTAT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Ruan M, Xu F, Li N, Yu J, Teng F, Tang J, Huang C, Zhu H. Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1. PLoS Biol 2024 22(10) e3002841  [ PubMed ID = 39436954 ] [ RRC reference ] Li N, Hua B, Chen Q, Teng F, Ruan M, Zhu M, Zhang L, Huo Y, Liu H, Zhuang M, Shen H, Zhu H. A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk. Cell Rep 2022 40(4) 111140  [ PubMed ID = 35905721 ] [ RRC reference ] Van Veldhoven PP, Baes M. Peroxisome deficient invertebrate and vertebrate animal models. Front Physiol 2013 4 335  [ PubMed ID = 24319432 ] [ RRC reference ] Wang R, Kniazeva M, Han M. Peroxisome protein transportation affects metabolism of branched-chain fatty acids that critically impact growth and development of C. elegans. PLoS One 2013 8(9) e76270  [ PubMed ID = 24086720 ] [ RRC reference ]