分離済み変異体

tm491

Allele Nametm491
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0414.2
Gene Namernt-1
Worm BaseAllele Name tm491
Gene Name rnt-1
Sequence B0414.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. J. Lee: short body length.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14468/14469-15314/15315 (846 bp deletion)
ChromosomeI
Putative gene structurejoin (13159..13173, 13218..13335, 13592..13711, 14513..14586, 15563..15679, 16289..16347, 16400..16518, 16571..16800)
Map position0.45
Balancer
Map position of balancer
Sequence of primersExtFwd:GCAAAAGTGCATCGACAAGT,IntRev:CAGGCGTTCGGATAATATCA,IntFwd:TTTGCGGTTTGTCGGGCGGT,ExtRev:CAAAAAATCGTACCGGTGGT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Lee K, Shim J, Lee J, Lee J.
Identification of genes interacting with rnt-1 through large-scale RNAi screening in Caenorhabditis elegans.
G3 (Bethesda) 2013 3(10) 1779-84 
[ PubMed ID = 23979934 ] [ RRC reference ]

Lee K, Shim J, Bae J, Kim YJ, Lee J.
Stabilization of RNT-1 protein, runt-related transcription factor (RUNX) protein homolog of Caenorhabditis elegans, by oxidative stress through mitogen-activated protein kinase pathway.
J Biol Chem 2012 287(13) 10444-10452 
[ PubMed ID = 22308034 ] [ RRC reference ]

Shim J, Lee J.
Regulation of rnt-1 expression mediated by the opposing effects of BRO-1 and DBL-1 in the nematode Caenorhabditis elegans.
Biochem Biophys Res Commun 2008 367(1) 130-6 
[ PubMed ID = 18158917 ] [ RRC reference ]

Kagoshima H, Sawa H, Mitani S, Bürglin TR, Shigesada K, Kohara Y.
The C. elegans RUNX transcription factor RNT-1/MAB-2 is required for asymmetrical cell division of the T blast cell.
Dev Biol 2005 287(2) 262-73 
[ PubMed ID = 16226243 ] [ RRC reference ]