分離済み変異体

tm487

Allele Nametm487
BalanceCompleted
OutCrossNot Accepted
Sequence NameC46C2.1
Gene Namewnk-1
Worm BaseAllele Name tm487 (x1)
Gene Name wnk-1
Sequence C46C2.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 17333/17334-18095/18096 (762 bp deletion)
ChromosomeIV
Putative gene structurejoin(14510..14554, 15442..15520, 15825..15894, 16489..16573, 16911..17347, 17403..17704, 17774..18099, 18147..19391, 19680..20378, 20430..21194, 21281..21712, 22290..22772, 23560..23612, 23668..23872, 24447..24776)
Map position4.11
Balancermec-3 (e1338) IV,nT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:TCGATGAACTACATCCAGCA,IntFwd:CAAGAGAATCCCACGTTAGT,IntRev:CGATGATCTCGATCTCTTCT,ExtRev:TCTTCCTCCTCTTTTGCTCT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Ray S, Gurung P, Manning RS, Kravchuk AA, Singhvi A.
Neuron cilia restrain glial KCC-3 to a microdomain to regulate multisensory processing.
Cell Rep 2024 43(3) 113844 
[ PubMed ID = 38421867 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Hisamoto N, Moriguchi T, Urushiyama S, Mitani S, Shibuya H, Matsumoto K.
Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity.
EMBO Rep 2008 9(1) 70-5 
[ PubMed ID = 18049475 ] [ RRC reference ]