分離済み変異体

tm4867

Allele Nametm4867
Allele Type通常株
Sequence NameC15H11.2
Gene Namegnrr-2
Worm BaseAllele Name tm4867
Gene Name gnrr-2
Sequence C15H11.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26473/26474-26950/26951 (477 bp deletion)
ChromosomeV
Putative gene structurejoin(24567..24806, 25200..25315, 25780..25939, 26497..26673, 26724..26844, 26893..27130, 27297..27384)
Map position6.29
Balancer
Map position of balancer
Sequence of primersExtFwd:ATGGGCAAAACGCCCGTTAA,IntFwd:GTACCGTATATTTGGGTCCA,ExtRev:GAATCGAATCCCCTGGCATC,IntRev:GCCCTGTCATCATTATCCCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Ma L, Kuhn J, Chang YT, Elnatan D, Luxton GWG, Starr DA.
FLN-2 functions in parallel to LINC complexes and Cdc42/actin pathways during P-cell nuclear migration through constricted spaces in Caenorhabditis elegans.
bioRxiv 2023   
[ PubMed ID = 37577634 ] [ RRC reference ]

Kishner M, Habaz L, Meshnik L, Meidan TD, Polonsky A, Ben-Zvi A.
Gonadotropin-releasing hormone-like receptor 2 inversely regulates somatic proteostasis and reproduction in Caenorhabditis elegans.
Front Cell Dev Biol 2022 10 951199 
[ PubMed ID = 36105349 ] [ RRC reference ]

Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K.
In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding.
PLoS Biol 2013 11(11) e1001712 
[ PubMed ID = 24260022 ] [ RRC reference ]