分離済み変異体

tm4856

Allele Nametm4856
BalanceNot Required
OutCrossNot Accepted
Sequence NameC17C3.18
Gene Nameins-13
Worm BaseAllele Name tm4856
Gene Name ins-13
Sequence C17C3.18
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 14495/14496-14871/14872 (376 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(14476..14610, 14656..14742))
Map position-1.17
Balancer
Map position of balancer
Sequence of primersIntRev:CGGGTTAGCTCAAGGATGTT,ExtFwd:GATTGGCAGTGTAGTGGGTT,ExtRev:CTTCGCACATCCTGGACTGA,IntFwd:ACATGGATACCCAAGGGTTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q.
An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.
PLoS Genet 2014 10(3) e1004225 
[ PubMed ID = 24675767 ] [ RRC reference ]

Hung WL, Hwang C, Gao S, Liao EH, Chitturi J, Wang Y, Li H, Stigloher C, Bessereau JL, Zhen M.
Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development.
EMBO J 2013 32(12) 1745-60 
[ PubMed ID = 23665919 ] [ RRC reference ]