分離済み変異体

tm4845

Allele Nametm4845
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK177.2
Gene NameZK177.2
Worm BaseAllele Name tm4845
Gene Name ZK177.2
Sequence ZK177.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 17936/17937-AAAA-18148/18149 (212 bp deletion + 4 bp insertion)
ChromosomeII
Putative gene structurejoin(17797..18496, 18547..18635, 18679..18780)
Map position-1.24
Balancer
Map position of balancer
Sequence of primersExtFwd:GCACGAGCAACCAAACCCGA,ExtRev:GTGATACACCGTCTGTAGTC,IntFwd:AACCCGAGTCTAGTATGGAG,IntRev:GCTGGTTCTCCAATCGGCCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Liachko NF, McMillan PJ, Guthrie CR, Bird TD, Leverenz JB, Kraemer BC.
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Ann Neurol 2013 74(1) 39-52 
[ PubMed ID = 23424178 ] [ RRC reference ]