分離済み変異体

tm4796

Allele Nametm4796
BalanceNot Required
OutCrossNot Accepted
Sequence NameY57G11C.37
Gene NameY57G11C.37
Worm BaseAllele Name tm4796
Gene Name Y57G11C.37
Sequence Y57G11C.37
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 33546/33547-TTTTTTTTTTTTTTCC-34207/34208 (661 bp deletion + 16 bp insertion)
ChromosomeIV
Putative gene structurejoin(26979..27130, 28669..29038, 29876..30034, 31349..31595, 32456..32543, 32591..32712, 32759..32889, 33925..34590, 36558..36788, 37500..37718)
Map position12.32
Balancer
Map position of balancer
Sequence of primersExtFwd:GTCGATTTTAGCTTCCGTGG,IntFwd:CCGTTGTGTGATTTCATAGC,ExtRev:GCTTACGGCCCACTTTCTAT,IntRev:ACGTTATCCATGCAACAGTC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zou W, Fan Y, Liu J, Cheng H, Hong H, Al-Sheikh U, Li S, Zhu L, Li R, He L, Tang YQ, Zhao G, Zhang Y, Wang F, Zhan R, Zheng X, Kang L.
Anoctamin-1 is a core component of a mechanosensory anion channel complex in C. elegans.
Nat Commun 2025 16(1) 1680 
[ PubMed ID = 39956854 ] [ RRC reference ]

Kim KW, Tang NH, Piggott CA, Andrusiak MG, Park S, Zhu M, Kurup N, Cherra SJ 3rd, Wu Z, Chisholm AD, Jin Y.
Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration.
Elife 2018 7  
[ PubMed ID = 30461420 ] [ RRC reference ]

Wang Y, Alam T, Hill-Harfe K, Lopez AJ, Leung CK, Iribarne D, Bruggeman B, Miyamoto MM, Harfe BD, Choe KP.
Phylogenetic, expression, and functional analyses of anoctamin homologs in Caenorhabditis elegans.
Am J Physiol Regul Integr Comp Physiol 2013 305(11) R1376-89 
[ PubMed ID = 24049119 ] [ RRC reference ]