分離済み変異体

tm4763

Allele Nametm4763
BalanceNot Required
OutCrossNot Accepted
Sequence NameC25G6.5
Gene Namenpr-11
Worm BaseAllele Name tm4763
Gene Name npr-11
Sequence C25G6.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 21570/21571-CTTTTCAGTTTTCTGAAAACATGTTAACTGGTATTATATTAACCAGTATGTAGG-21901/21902 (331 bp deletion + 54 bp insertion)
ChromosomeX
Putative gene structurecomplement(join(17692..17854,18669..18836,19926..20086, 20136..20232, 20881..21050, 21454..21652,21704..21852, 21908..22057,22172..22282))
Map position-18.47
Balancer
Map position of balancer
Sequence of primersExtFwd:CCCTTGACTATCGTCACACC,IntFwd:AGGAGCTGATACATGAAGCT,ExtRev:CTCTTATAACCGACCGACTA,IntRev:CCACTAGTCTGGATGCTCAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Otarigho B, Butts AF, Aballay A.
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans.
Elife 2024 12  
[ PubMed ID = 38446031 ] [ RRC reference ]

Peng JY, Liu X, Zeng XT, Hao Y, Zhang JH, Li Q, Tong XJ.
Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans.
Cell Rep 2023 42(6) 112598 
[ PubMed ID = 37289584 ] [ RRC reference ]

Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R.
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans.
J Neurosci 2013 33(35) 14107-16 
[ PubMed ID = 23986246 ] [ RRC reference ]