分離済み変異体

tm4756

Allele Nametm4756
BalanceNot Required
OutCrossNot Accepted
Sequence NameR102.5
Gene NameR102.5
Worm BaseAllele Name tm4756
Gene Name R102.5
Sequence R102.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 11730/11731-12309/12310 (579 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(10746..10850, 11013..11695, 11752..12198, 12284..12344))
Map position4.67
Balancer
Map position of balancer
Sequence of primersExtRev:GCAGTAACCAGTGCTTAGTG,IntRev:CATACGACCTCACTCTTCTC,ExtFwd:GCTTGAACGGTTTCTATGGT,IntFwd:AAACCGCACCTCATGCAGAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Sasaki T, Kushida Y, Norizuki T, Kosako H, Sato K, Sato M.
ALLO-1- and IKKE-1-dependent positive feedback mechanism promotes the initiation of paternal mitochondrial autophagy.
Nat Commun 2024 15(1) 1460 
[ PubMed ID = 38368448 ] [ RRC reference ]

Rubio-Peña K, Al Rawi S, Husson F, Lam F, Merlet J, Galy V.
Mitophagy of polarized sperm-derived mitochondria after fertilization.
iScience 2021 24(1) 102029 
[ PubMed ID = 33506190 ] [ RRC reference ]

Sato M, Sato K, Tomura K, Kosako H, Sato K.
The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans.
Nat Cell Biol 2018 20(1) 81-91 
[ PubMed ID = 29255173 ] [ RRC reference ]