分離済み変異体

tm4743

Allele Nametm4743
BalanceCompleted
OutCrossNot Accepted
Sequence NameVF36H2L.1
Gene Nameaph-1
Worm BaseAllele Name tm4743 (x1)
Gene Name aph-1
Sequence VF36H2L.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3061/3062-3666/3667 (605 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(2747..3013, 3097..3484, 3743..3901, 3950..4062))
Map position3.69
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtFwd:ACGGCAAAGACGAGTACATG,IntRev:CTCGATCCACTTCATCGCTT,IntFwd:GAAGCCACGAGAGTTGAGAG,ExtRev:CAATGCGTAATTCACTGCCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Brinkley DM, Smith KC, Fink EC, Kwen W, Yoo NH, West Z, Sullivan NL, Farthing AS, Hale VA, Goutte C.
Notch signaling without the APH-2/nicastrin subunit of gamma secretase in Caenorhabditis elegans germline stem cells.
Genetics 2024 227(3)  
[ PubMed ID = 38717968 ] [ RRC reference ]