Home > 分離済み変異体 > tm4687

分離済み変異体

Allele Name		tm4687
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C23F12.1
Gene Name		fln-2
Worm Base	Allele Name	tm4687
	Gene Name	fln-2
	Sequence	C23F12.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		35346/35347-35893/35894 (547 bp deletion)
Chromosome		X
Putative gene structure		join(11872..12003, 12940..13266, 13310..13621, 13748..13901, 13948..14028, 14204..14286, 14410..14473, 14731..14843, 14888..14935, 16614..16706, 17487..17711, 17758..17844, 18231..18320, 19462..19650, 20094..20226, 20514..20620, 20659..20766, 21331..21472, 21523..21669, 21991..22074, 23965..24114, 26418..26536, 26980..27086, 27300..27574, 28035..28106, 28584..28674, 28887..28963, 29164..29259, 29622..29797, 30460..30659, 30926..31018, 31095..32725, 32780..33034, 33085..33267, 33549..33751, 34577..34703, 34881..35102, 35150..35317, 35364..35474, 35543..35806, 35917..36396, 36555..36635, 36683..36805, 36942..37652, 37703..37849, 38118..38342, 38395..38571, 38644..39057, 39108..39225, 39345..39491, 39543..40199, 40247..40412, 40570..[B0272]9158)
Map position		1.2
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GTCACATAGATTCCCCGCCA,IntFwd:TCCCCGCCAAAACTACCGTT,ExtRev:TCTCTGGCCAATCCAGTCTT,IntRev:GGCGTCTTTTGGAGAACCGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Ma L, Kuhn J, Chang YT, Elnatan D, Luxton GWG, Starr DA. FLN-2 functions in parallel to linker of nucleoskeleton and cytoskeleton complexes and CDC-42/actin pathways during P-cell nuclear migration through constricted spaces in Caenorhabditis elegans. Genetics 2024 227(3)   [ PubMed ID = 38797871 ] [ RRC reference ] Ma L, Kuhn J, Chang YT, Elnatan D, Luxton GWG, Starr DA. FLN-2 functions in parallel to LINC complexes and Cdc42/actin pathways during P-cell nuclear migration through constricted spaces in Caenorhabditis elegans. bioRxiv 2023    [ PubMed ID = 37577634 ] [ RRC reference ] Zhao Y, Wang H, Poole RJ, Gems D. A fln-2 mutation affects lethal pathology and lifespan in C. elegans. Nat Commun 2019 10(1) 5087  [ PubMed ID = 31704915 ] [ RRC reference ]