Home > 分離済み変異体 > tm4634

分離済み変異体

Allele Name		tm4634
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y34D9A.6
Gene Name		glrx-10
Worm Base	Allele Name	tm4634
	Gene Name	glrx-10
	Sequence	Y34D9A.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		31458/31459-ACACACACGATTCG-31787/31788 (329 bp deletion + 14 bp insertion)
Chromosome		I
Putative gene structure		join(31479..31562, 32281..32514)
Map position		-17.27
Balancer
Map position of balancer
Sequence of primers		ExtRev:GGCAGCCGATTGTCAATGGA,IntRev:TGCCAGAACCCCGTGACAGA,ExtFwd:CCGCACGGCGGTAATTTCGA,IntFwd:TCCCGAATTTTCCTCGCCTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Johnson WM, Golczak M, Choe K, Curran PL, Miller OG, Yao C, Wang W, Lin J, Milkovic NM, Ray A, Ravindranath V, Zhu X, Wilson MA, Wilson-Delfosse AL, Chen SG, Mieyal JJ. Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease. Biochemistry 2016 55(32) 4519-32  [ PubMed ID = 26894491 ] [ RRC reference ] Johnson WM, Yao C, Siedlak SL, Wang W, Zhu X, Caldwell GA, Wilson-Delfosse AL, Mieyal JJ, Chen SG. Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease. Hum Mol Genet 2015 24(5) 1322-35  [ PubMed ID = 25355420 ] [ RRC reference ]