分離済み変異体

tm463

Allele Nametm463
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0286.2
Gene Namelat-2
Worm BaseAllele Name tm463
Gene Name lat-2
Sequence B0286.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Y-K. Paik: dauer formed on daumone plate. Dr. M. Peter: does not suppress par-2 (RNAi).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2402/2403-3780/3781 (1378 bp deletion)
ChromosomeII
Putative gene structurejoin(1681..1771, 1817..1972, 2391..2674, 3380..3489, 3535..3732, 4020..4217, 4667..4725, 5122..5347, 5724..6049, 6139..6226, 6598..7038, 7540..7617, 8073..8296, 8610..8853, 8900..9764, 10463..10690, 10844..11033, 11079..11206, 11298..11513)
Map position-4.8
Balancer
Map position of balancer
Sequence of primersExtFwd:GGCAGACGTTTTTGTGACTA,IntFwd:CGTAGGGCTTACCTTTTAGA,IntRev:CGAGACGGACTAAGTATTAG,ExtRev:AACGGAATGAATGCGCAACC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Govek KW, Nicodemus P, Lin Y, Crawford J, Saturnino AB, Cui H, Zoga K, Hart MP, Camara PG.
CAJAL enables analysis and integration of single-cell morphological data using metric geometry.
Nat Commun 2023 14(1) 3672 
[ PubMed ID = 37339989 ] [ RRC reference ]

Langenhan T, Prömel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, Kohara Y, Avery L, Vakonakis I, Schnabel R, Russ AP.
Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo.
Dev Cell 2009 17(4) 494-504 
[ PubMed ID = 19853563 ] [ RRC reference ]

Guest M, Bull K, Walker RJ, Amliwala K, O'Connor V, Harder A, Holden-Dye L, Hopper NA.
The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans.
Int J Parasitol 2007 37(14) 1577-88 
[ PubMed ID = 17583712 ] [ RRC reference ]

Labbé JC, Pacquelet A, Marty T, Gotta M.
A genomewide screen for suppressors of par-2 uncovers potential regulators of PAR protein-dependent cell polarity in Caenorhabditis elegans.
Genetics 2006 174(1) 285-95 
[ PubMed ID = 16816419 ] [ RRC reference ]