分離済み変異体

tm4613

Allele Nametm4613
Allele Type通常株
Sequence NameY53F4B.3
Gene NameY53F4B.3
Worm BaseAllele Name tm4613
Gene Name Y53F4B.3
Sequence Y53F4B.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 17466/17467-TTTCCCTGAAAAAAAAGTGA-18173/18174 (707 bp deletion + 20 bp insertion)
ChromosomeII
Putative gene structurecomplement(join(17553..17809, 17859..17943, 18000..18197))
Map position23.84
Balancer
Map position of balancer
Sequence of primersIntFwd:ATTCCGAAGGACCTTCCTGA,ExtFwd:CACGCGAAACCGGTCTCAAC,IntRev:GTGTTTGCGTCCAGAGCGGA,ExtRev:CGTCTGCCTTTGCGCGTGAT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Bellelli R, Youds J, Borel V, Svendsen J, Pavicic-Kaltenbrunner V, Boulton SJ.
Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication.
Cell Rep 2020 31(8) 107675 
[ PubMed ID = 32460026 ] [ RRC reference ]

Meier B, Volkova NV, Hong Y, Schofield P, Campbell PJ, Gerstung M, Gartner A.
Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers.
Genome Res 2018 28(5) 666-675 
[ PubMed ID = 29636374 ] [ RRC reference ]