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分離済み変異体

Allele Name		tm458
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F31A3.2
Gene Name		hlh-28
Worm Base	Allele Name	tm458
	Gene Name	hlh-28
	Sequence	F31A3.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. R. Lin, Dr. M. Maduro: normal cell division during 8-30 cell stage. Dr. P. Sengupta: normal dye-filling into sensory neurons. Dr. J. Priess: Dev. Cell 8, 867-879 (2005). Dr. C.M. Johnson: BBA 1769, 5 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		19745/19746-21019/21020 (1274 bp deletion)
Chromosome		X
Putative gene structure		join(18012..18080, 19345..19514, 19567..19791, 19841..20165)
Map position		24.35
Balancer
Map position of balancer
Sequence of primers		ExtRev:GACGTAAGCCGGAAGGAGTT,IntRev:TTTTAACACCGACGACAACG,IntFwd:CGCGAGCCTTGTCATGGGAA,ExtFwd:TCCTATGCCACGCTTAATAG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication McMiller TL, Sims D, Lee T, Williams T, Johnson CM. Molecular characterization of the Caenorhabditis elegans REF-1 family member, hlh-29/hlh-28. Biochim Biophys Acta 2007 1769(1) 5-19  [ PubMed ID = 17258327 ] [ RRC reference ] Lanjuin A, Claggett J, Shibuya M, Hunter CP, Sengupta P. Regulation of neuronal lineage decisions by the HES-related bHLH protein REF-1. Dev Biol 2006 290(1) 139-51  [ PubMed ID = 16376329 ] [ RRC reference ] Neves A, Priess JR. The REF-1 family of bHLH transcription factors pattern C. elegans embryos through Notch-dependent and Notch-independent pathways. Dev Cell 2005 8(6) 867-79  [ PubMed ID = 15935776 ] [ RRC reference ]