Home > 分離済み変異体 > tm4575

分離済み変異体

Allele Name		tm4575
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F35G12.4
Gene Name		F35G12.4
Worm Base	Allele Name	tm4575
	Gene Name	F35G12.4
	Sequence	F35G12.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		13455/13456-13921/13922 (466 bp deletion)
Chromosome		III
Putative gene structure		join(12675..12860, 12914..13040, 13092..13183, 13231..13425, 13472..13678, 13726..13913, 13958..14130, 14176..14282, 14333..14431, 14485..14578, 14633..14780, 14832..15023, 15073..15155, 15198..15358)
Map position		-3.08
Balancer
Map position of balancer
Sequence of primers		ExtRev:CGTCTTTTGATGAAAGCCAC,IntRev:AGCGTCCAGCTCGTCCAAAG,ExtFwd:CGCGATGAGCACGAGTATTC,IntFwd:TCGTTCGGCTGTCAGTGCTC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Hodul M, Ganji R, Dahlberg CL, Raman M, Juo P. The WD40-repeat protein WDR-48 promotes the stability of the deubiquitinating enzyme USP-46 by inhibiting its ubiquitination and degradation. J Biol Chem 2020 295(33) 11776-11788  [ PubMed ID = 32587090 ] [ RRC reference ] Dahlberg CL, Juo P. The WD40-repeat proteins WDR-20 and WDR-48 bind and activate the deubiquitinating enzyme USP-46 to promote the abundance of the glutamate receptor GLR-1 in the ventral nerve cord of Caenorhabditis elegans. J Biol Chem 2014 289(6) 3444-56  [ PubMed ID = 24356955 ] [ RRC reference ]