分離済み変異体

tm4568

Allele Nametm4568
BalanceCompleted
OutCrossNot Accepted
Sequence NameF32H2.1
Gene Namegei-11
Worm BaseAllele Name tm4568 (x1)
Gene Name gei-11
Sequence F32H2.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3890/3891-GTAAATTT-4421/4422 (531 bp deletion + 8 bp insertion)
ChromosomeI
Putative gene structurejoin(3152..3229, 3279..3878, 3951..4177, 4223..4412, 4533..4817, 4896..5108, 5178..5332, 5388..5457, 5502..5726, 5784..6104, 6153..6362, 6411..6548, 6603..6725)
Map position3.35
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtRev:GAGTCTCATTCATATCCGGA,IntFwd:CCTAGAAAACCACGGTATGT,ExtFwd:TCCGCCGATATGTCCCTTGA,IntRev:AGGAGCACGTCTTCCGGATT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Cao W, Fan Q, Amparado G, Begic D, Godini R, Gopal S, Pocock R.
A nucleic acid binding protein map of germline regulation in Caenorhabditis elegans.
Nat Commun 2024 15(1) 6884 
[ PubMed ID = 39128930 ] [ RRC reference ]

Kudron M, Gevirtzman L, Victorsen A, Lear BC, Gao J, Xu J, Samanta S, Frink E, Tran-Pearson A, Huynh C, Vafeados D, Hammonds A, Fisher W, Wall M, Wesseling G, Hernandez V, Lin Z, Kasparian M, White K, Allada R, Gerstein M, Hillier L, Celniker SE, Reinke V, Waterston RH.
Binding profiles for 954 Drosophila and C. elegans transcription factors reveal tissue specific regulatory relationships.
bioRxiv 2024   
[ PubMed ID = 38293065 ] [ RRC reference ]

Weng C, Kosalka J, Berkyurek AC, Stempor P, Feng X, Mao H, Zeng C, Li WJ, Yan YH, Dong MQ, Morero NR, Zuliani C, Barabas O, Ahringer J, Guang S, Miska EA.
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans.
Genes Dev 2019 33(1-2) 90-102 
[ PubMed ID = 30567997 ] [ RRC reference ]

Kasper DM, Wang G, Gardner KE, Johnstone TG, Reinke V.
The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance.
Dev Cell 2014 31(2) 145-58 
[ PubMed ID = 25373775 ] [ RRC reference ]