分離済み変異体

tm4559

Allele Nametm4559
BalanceNot Required
OutCrossNot Accepted
Sequence NameH22K11.1
Gene Nameasp-3
Worm BaseAllele Name tm4559
Gene Name asp-3
Sequence H22K11.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19550/19551-CCTT-19785/19786 (235 bp deletion + 4 bp insertion)
ChromosomeX
Putative gene structurejoin(19463..19521, 19602..19878, 19930..20034, 20088..20843)
Map position-2.43
Balancer
Map position of balancer
Sequence of primersExtRev:CCCATGAATCCAGAGAGGCA,IntRev:GGTGGATCCTCCGTTTCCGT,ExtFwd:GTCGCCTTGGCTTCTGCCAT,IntFwd:TTGGCTTCTGCCATCCAGAG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Dai W, Zhai Y, Yang F, Chen W, Liu C, Tian Y, Huang F, Cai M, Zheng L, Cheng W, Chen W, Zhang J.
Different concentrations of 2-Undecanone triggers repellent and nematicidal responses in Caenorhabditis elegans.
Sci Rep 2025 15(1) 14186 
[ PubMed ID = 40269070 ] [ RRC reference ]

Cheng W, Dai W, Chen W, Xue H, Zhao Z, Jiang Z, Li H, Liu J, Huang F, Cai M, Zheng L, Yu Z, Peng D, Zhang J.
Nematodes exposed to furfural acetone exhibit a species-specific vacuolar H+-ATPase response.
Ecotoxicol Environ Saf 2024 288 117407 
[ PubMed ID = 39603226 ] [ RRC reference ]

Zhang F, Peng D, Cheng C, Zhou W, Ju S, Wan D, Yu Z, Shi J, Deng Y, Wang F, Ye X, Hu Z, Lin J, Ruan L, Sun M.
Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1).
PLoS Pathog 2016 12(1) e1005389 
[ PubMed ID = 26795495 ] [ RRC reference ]

Geng X, Harry BL, Zhou Q, Skeen-Gaar RR, Ge X, Lee ES, Mitani S, Xue D.
Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2012 109(45) 18465-70 
[ PubMed ID = 23091037 ] [ RRC reference ]