分離済み変異体

tm4536

Allele Nametm4536
BalanceCompleted
OutCrossNot Accepted
Sequence NameF09E5.5
Gene Namesec-6
Worm BaseAllele Name tm4536 (x1)
Gene Name sec-6
Sequence F09E5.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 20077/20078-20400/20401 (323 bp deletion)
ChromosomeII
Putative gene structurejoin(19705..19815, 19873..19985, 20033..20327, 20381..20476, 20824..20891, 21215..21521, 21573..21818, 22360..22452, 29277..29370, 29421..29491, 29955..30163, 31329..31553, 31605..31725, 31776..32117)
Map position-1.79
BalancermIn1 [e128 mIs14]
Map position of balancer
Sequence of primersExtFwd:GTGACGATCGAAGGACAGAG,IntFwd:GAGCTTTGACGGACCTGCGA,ExtRev:CTCGACAGAACAGGACTATC,IntRev:ATAGCCTGTGCATTGATCCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Pushpa K, Dagar S, Kumar H, Pathak D, Mylavarapu SVS.
The exocyst complex regulates C. elegans germline stem cell proliferation by controlling membrane Notch levels.
Development 2021 148(15)  
[ PubMed ID = 34338279 ] [ RRC reference ]

Kumar H, Pushpa K, Kumari A, Verma K, Pergu R, Mylavarapu SVS.
The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge.
J Cell Sci 2019 132(14)  
[ PubMed ID = 31221728 ] [ RRC reference ]