分離済み変異体

tm4519

Allele Nametm4519
BalanceCompleted
OutCrossNot Accepted
Sequence NameH04D03.1
Gene NameH04D03.1
Worm BaseAllele Name tm4519 (x1)
Gene Name H04D03.1
Sequence H04D03.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 7000/7001-7403/7404 (403 bp deletion)
ChromosomeIII
Putative gene structurejoin(6736..6795, 6854..7195, 7310..7522)
Map position2.5
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersExtRev:CGTGGCTTGTCCACAGTGAC,IntFwd:TAGTCCCTGCCCCTACTCAC,ExtFwd:GCGGTGGTTGCGAAATAGTC,IntRev:TCTCGCTTCCGGTCCTTAGA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Florica RO, Hipolito V, Bautista S, Anvari H, Rapp C, El-Rass S, Asgharian A, Antonescu CN, Killeen MT.
The ENU-3 protein family members function in the Wnt pathway parallel to UNC-6/Netrin to promote motor neuron axon outgrowth in C. elegans.
Dev Biol 2017 430(1) 249-261 
[ PubMed ID = 28694018 ] [ RRC reference ]

Yee C, Florica R, Fillingham J, Killeen MT.
ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans.
Dev Dyn 2014 243(3) 459-67 
[ PubMed ID = 24123761 ] [ RRC reference ]

Yee CS, Sybingco SS, Serdetchania V, Kholkina G, Bueno de Mesquita M, Naqvi Z, Park SH, Lam K, Killeen MT.
ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.
Dev Biol 2011 352(2) 243-53 
[ PubMed ID = 21295567 ] [ RRC reference ]