分離済み変異体

tm4515

Allele Nametm4515
BalanceNot Required
OutCrossNot Accepted
Sequence NameK10G6.2
Gene Namedos-2
Worm BaseAllele Name tm4515
Gene Name dos-2
Sequence K10G6.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 22045/22046-22422/22423 (377 bp deletion)
ChromosomeII
Putative gene structurejoin(21605..21668, 21911..22043, 22089..22197, 22262..22362, 22605..22819, 22914..23119)
Map position-5.9
Balancer
Map position of balancer
Sequence of primersExtFwd:CTAGATGTAGAGCAAGCGCT,IntRev:CTCACCCAGACCATCATATC,IntFwd:TATTCGCCGGCGTCATTGAA,ExtRev:CAAAGGTCCGATGTGTTGCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Daniele T, Cury J, Morin MC, Ahier A, Isaia D, Jarriault S.
Essential and dual effects of Notch activity on a natural transdifferentiation event.
Nat Commun 2025 16(1) 75 
[ PubMed ID = 39746948 ] [ RRC reference ]

Sorkaç A, DiIorio MA, O'Hern PJ, Baskoylu SN, Graham HK, Hart AC.
LIN-12/Notch Regulates GABA Signaling at the Caenorhabditis elegans Neuromuscular Junction.
G3 (Bethesda) 2018 8(8) 2825-2832 
[ PubMed ID = 29950427 ] [ RRC reference ]

Singh K, Chao MY, Somers GA, Komatsu H, Corkins ME, Larkins-Ford J, Tucey T, Dionne HM, Walsh MB, Beaumont EK, Hart DP, Lockery SR, Hart AC.
C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence.
Curr Biol 2011 21(10) 825-34 
[ PubMed ID = 21549604 ] [ RRC reference ]