Home > 分離済み変異体 > tm4477

分離済み変異体

Allele Name		tm4477
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C02F5.6
Gene Name		henn-1
Worm Base	Allele Name	tm4477
	Gene Name	henn-1
	Sequence	C02F5.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		7132/7133-7505/7506 (373 bp deletion)
Chromosome		III
Putative gene structure		join(6193..6234, 6422..6873, 6928..7086, 7137..7491, 7539..7652, 7726..7863)
Map position		-0.36
Balancer
Map position of balancer
Sequence of primers		IntRev:AATCAATCGGGATCCCAATC,IntFwd:CCTACGTCGAAGCTTACGAA,ExtRev:TTACCTACCGTTCTCGGTTC,ExtFwd:GGGAGCTCCATATGATAATG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Pastore B, Hertz HL, Tang W. The ribonuclease DISL-2 mediates piRNA degradation in C. elegans. Cell Rep 2025 44(10) 116430  [ PubMed ID = 41075248 ] [ RRC reference ] Pastore B, Hertz HL, Price IF, Tang W. pre-piRNA trimming and 2'-O-methylation protect piRNAs from 3' tailing and degradation in C. elegans. Cell Rep 2021 36(9) 109640  [ PubMed ID = 34469728 ] [ RRC reference ] Alberti C, Manzenreither RA, Sowemimo I, Burkard TR, Wang J, Mahofsky K, Ameres SL, Cochella L. Cell-type specific sequencing of microRNAs from complex animal tissues. Nat Methods 2018 15(4) 283-289  [ PubMed ID = 29481550 ] [ RRC reference ] Kim KW, Tang NH, Andrusiak MG, Wu Z, Chisholm AD, Jin Y. A Neuronal piRNA Pathway Inhibits Axon Regeneration in C. elegans. Neuron 2018 97(3) 511-519.e6  [ PubMed ID = 29395906 ] [ RRC reference ] Tang W, Tu S, Lee HC, Weng Z, Mello CC. The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans. Cell 2016 164(5) 974-84  [ PubMed ID = 26919432 ] [ RRC reference ] Billi AC, Freeberg MA, Day AM, Chun SY, Khivansara V, Kim JK. A conserved upstream motif orchestrates autonomous, germline-enriched expression of Caenorhabditis elegans piRNAs. PLoS Genet 2013 9(3) e1003392  [ PubMed ID = 23516384 ] [ RRC reference ] Billi AC, Alessi AF, Khivansara V, Han T, Freeberg M, Mitani S, Kim JK. The Caenorhabditis elegans HEN1 ortholog, HENN-1, methylates and stabilizes select subclasses of germline small RNAs. PLoS Genet 2012 8(4) e1002617  [ PubMed ID = 22548001 ] [ RRC reference ]