分離済み変異体

tm4457

Allele Nametm4457
BalanceNot Required
OutCrossNot Accepted
Sequence NameC13B9.4
Gene Namepdfr-1
Worm BaseAllele Name tm4457
Gene Name pdfr-1
Sequence C13B9.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15159/15160-15557/15558 (398 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(14812..14895,15034..15132,15181..15318, 15470..15559, 15607..15929, 15976..16132, 16179..16335, 16742..16845, 17132..17470, 17623..17747, 18800..18922, 19081..19126,19222..19290,19474..19554))
Map position-1.03
Balancer
Map position of balancer
Sequence of primersExtFwd:CTATACAGGAGTCGTACTCA,IntFwd:TTAAACCACGCAAGCCGTAC,ExtRev:AATGGCGAACGGTGGGTATA,IntRev:TTGCCCAAGCGAAAGCCTTA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Molina-García L, Colinas-Fischer S, Benavides-Laconcha S, Lin L, Clark E, Treloar NJ, García-Minaur-Ortíz B, Butts M, Barnes CP, Barrios A.
Conflict during learning reconfigures the neural representation of positive valence and approach behavior.
Curr Biol 2024 34(23) 5470-5483.e7 
[ PubMed ID = 39547234 ] [ RRC reference ]

Barrios A, Ghosh R, Fang C, Emmons SW, Barr MM.
PDF-1 neuropeptide signaling modulates a neural circuit for mate-searching behavior in C. elegans.
Nat Neurosci 2012 15(12) 1675-82 
[ PubMed ID = 23143519 ] [ RRC reference ]

Meelkop E, Temmerman L, Janssen T, Suetens N, Beets I, Van Rompay L, Shanmugam N, Husson SJ, Schoofs L.
PDF receptor signaling in Caenorhabditis elegans modulates locomotion and egg-laying.
Mol Cell Endocrinol 2012 361(1-2) 232-40 
[ PubMed ID = 22579613 ] [ RRC reference ]