分離済み変異体

tm4450

Allele Nametm4450
BalanceNot Required
OutCrossNot Accepted
Sequence NameH22K11.1
Gene Nameasp-3
Worm BaseAllele Name tm4450
Gene Name asp-3
Sequence H22K11.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 19552/19553-GGGGT-19720/19721 (168 bp deletion + 5 bp insertion)
ChromosomeX
Putative gene structurejoin(19463..19521, 19602..19878, 19930..20034, 20088..20843)
Map position-2.43
Balancer
Map position of balancer
Sequence of primersExtRev:CCCATGAATCCAGAGAGGCA,IntRev:GGTGGATCCTCCGTTTCCGT,ExtFwd:GTCGCCTTGGCTTCTGCCAT,IntFwd:TTGGCTTCTGCCATCCAGAG
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW.
Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
PLoS Genet 2019 15(8) e1008295 
[ PubMed ID = 31398187 ] [ RRC reference ]