Home > 分離済み変異体 > tm4368

分離済み変異体

Allele Name		tm4368
Balance		Completed
OutCross		Not Accepted
Sequence Name		F08F8.2
Gene Name		F08F8.2
Worm Base	Allele Name	tm4368 (x1)
	Gene Name	F08F8.2
	Sequence	F08F8.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		Let or Ste.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		20548/20549-21168/21169 (620 bp deletion)
Chromosome		III
Putative gene structure		join(20539..20618, 20711..20916, 20965..21131, 21186..21433, 21714..21890, 22057..22677, 22725..22878)
Map position		-0.75
Balancer		hT2,hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		ExtFwd:CCGATCAGTGTGGTGCGATC,IntFwd:GGTGCGATCAACATTAGCAA,ExtRev:AGGGTGTTCCAGCCAGCGTT,IntRev:CACACAGCATCTCTCGCCGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Stein KK, Golden A. The C. elegans eggshell. WormBook 2018 2018 1-36  [ PubMed ID = 26715360 ] [ RRC reference ] Ranji P, Rauthan M, Pitot C, Pilon M. Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria. PLoS One 2014 9(2) e100033  [ PubMed ID = 24918786 ] [ RRC reference ] Rauthan M, Ranji P, Aguilera Pradenas N, Pitot C, Pilon M. The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway. Proc Natl Acad Sci U S A 2013 110(15) 5981-6  [ PubMed ID = 23530189 ] [ RRC reference ] Shi Z, Ruvkun G. The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans. Proc Natl Acad Sci U S A 2012 109(12) 4568-73  [ PubMed ID = 22396595 ] [ RRC reference ]