分離済み変異体

tm4328

Allele Nametm4328
BalanceNot Required
OutCrossNot Accepted
Sequence NameF14B8.2
Gene Namesid-5
Worm BaseAllele Name tm4328
Gene Name sid-5
Sequence F14B8.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8131/8132-8387/8388 (256 bp deletion)
ChromosomeX
Putative gene structurejoin(8068..8121, 8167..8316)
Map position-2
Balancer
Map position of balancer
Sequence of primersExtFwd:ATCTTATTTCCCGCGTACTC,IntRev:CTAAGACCAACATCCAAGCT,ExtRev:GAGGTTTAGTTGAGCGCGGA,IntFwd:GCGTACTCCTCTCGGTCAAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Yoshida K, Suehiro Y, Dejima K, Yoshina S, Mitani S.
Distinct pathways for export of silencing RNA in Caenorhabditis elegans systemic RNAi.
iScience 2023 26(10) 108067 
[ PubMed ID = 37854694 ] [ RRC reference ]

Dejima K, Imae R, Suehiro Y, Yoshida K, Mitani S.
An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegans.
iScience 2023 26(6) 106930 
[ PubMed ID = 37305693 ] [ RRC reference ]

Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ortíz-Severín J, Varas MA, Chávez FP, Calixto A.
Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans.
mBio 2017 8(5)  
[ PubMed ID = 29018118 ] [ RRC reference ]

Hinas A, Wright AJ, Hunter CP.
SID-5 is an endosome-associated protein required for efficient systemic RNAi in C. elegans.
Curr Biol 2012 22(20) 1938-43 
[ PubMed ID = 22981770 ] [ RRC reference ]