分離済み変異体

tm4300

Allele Nametm4300
BalanceNot Required
OutCrossNot Accepted
Sequence NameY105C5B.2
Gene Namegcy-25
Worm BaseAllele Name tm4300
Gene Name gcy-25
Sequence Y105C5B.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 11322/11323-TTTAGCAAAAA-11702/11703 (380 bp deletion + 11 bp insertion)
ChromosomeIV
Putative gene structurejoin(9237..9376, 9773..9958, 10602..10692, 11203..11350, 11400..11508, 11878..12050, 12102..12490, 13159..13500, 13791..13862, 13916..14095, 14527..14713, 15519..15677, 15866..16076, 16608..16751, 16997..17120, 17518..17691, 17822..17931, 18108..18261, 18511..18648, 19728..19772)
Map position14.45
Balancer
Map position of balancer
Sequence of primersExtFwd:GGCTTGCGAAATGTTAGTGT,IntFwd:CAGTACGTACTAAGTGGATC,ExtRev:TTGAGGGAGGGAATTCCTGA,IntRev:GCGAACTCCAAATGCTAATC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mok CA, Healey MP, Shekhar T, Leroux MR, Héon E, Zhen M.
Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans.
PLoS Genet 2011 7(10) e1002335 
[ PubMed ID = 22022287 ] [ RRC reference ]

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM 3rd, Horvitz HR, Sternberg PW, Ringstad N.
Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2011 108(1) 254-9 
[ PubMed ID = 21173231 ] [ RRC reference ]