分離済み変異体

tm4275

Allele Nametm4275
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0414.8
Gene NameB0414.8
Worm BaseAllele Name tm4275
Gene Name B0414.8
Sequence B0414.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 34926/34927-35193/35194 (267 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(32498..32650, 33051..33209, 33256..33337, 33554..33652, 33706..34003, 34070..34223, 34294..34623, 34672..35103, 35163..35324, 35376..35550, 35594..35652))
Map position0.46
Balancer
Map position of balancer
Sequence of primersIntRev:GTCCTGGAGACACCATCGAT,IntFwd:CAGATTTGCAAGAGCGGTCT,ExtRev:CGCGCAATGATGTTCCACAA,ExtFwd:TCGCTAGCTGTGAACAAGAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Topalidou I, Cattin-Ortolá J, Pappas AL, Cooper K, Merrihew GE, MacCoss MJ, Ailion M.
The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles.
PLoS Genet 2016 12(5) e1006074 
[ PubMed ID = 27191843 ] [ RRC reference ]

Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S.
The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology.
Mol Biol Cell 2011 22(14) 2564-78 
[ PubMed ID = 21613545 ] [ RRC reference ]