分離済み変異体

tm4218

Allele Nametm4218
BalanceNot Required
OutCrossNot Accepted
Sequence NameC41G11.4
Gene Namegnrr-4
Worm BaseAllele Name tm4218
Gene Name gnrr-4
Sequence C41G11.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 23495/23496-TCTTTT-23850/23851 (355 bp deletion + 6 bp insertion)
ChromosomeX
Putative gene structurecomplement(join(21903..22159,22212..22313,22397..22533, 23130..23269, 23316..23402, 23657..23774, 23821..23957, 24005..24142, 24706..24838, 25090..25160, 25217..25273))
Map position-4.38
Balancer
Map position of balancer
Sequence of primersExtFwd:GGAGGTTTGTATGACGTTAC,IntFwd:GAGCGGAGGAGCTTTTGTAC,ExtRev:TCGGCAAAGAAGGGTACTTA,IntRev:CGATACTTTGATCTGAGCAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Chai CM, Park H, Sternberg PW.
Brain-wide bidirectional neuropeptide modulation of individual neuron classes regulates a developmental decision.
Curr Biol 2022 32(15) 3365-3373.e6 
[ PubMed ID = 35679871 ] [ RRC reference ]

Kishner M, Habaz L, Meshnik L, Meidan TD, Polonsky A, Ben-Zvi A.
Gonadotropin-releasing hormone-like receptor 2 inversely regulates somatic proteostasis and reproduction in Caenorhabditis elegans.
Front Cell Dev Biol 2022 10 951199 
[ PubMed ID = 36105349 ] [ RRC reference ]